| Author | Year | Level of evidence | Adjuvant systemic treatment type | Total number of patients | Number of patients systemic treatment/No systemic treatment | Male/female | Average age in years (range) |
| Yu et al. [2] | 2012 | IV | Post-operative oral bisphosphonates | 16 | 16/0 | 7/9 | 38 (27 - 78) |
| Xu et al. [1] | 2012 | IV | Peri-operative IV bisphosphonates | 102 | 37/65 | 36/66 | 32.7 (11 - 65) |
| Tse et al. [4] | 2008 | IV | Peri-operative IV and oral bisphosphonates | 44 | 24/20 | 27/17 | 36 (19 - 62) |
| Cheng et al. [3] | 2004 | IV | Preoperative IV bisphosphonates | 18 | 12/6 | NR | NR |
| Totals | - | - | - | 180 | 89/91 | 70/92 | 34.1* (11 - 78) |